“Long-term data from the KEYNOTE-001 study showed that the anti–programmed death 1 (PD-1) antibody pembrolizumab produces durable responses in metastatic melanoma patients. These results were presented at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting held May 29 to June 2 in Chicago.
Pembrolizumab is approved as a second-line therapy for metastatic melanoma following treatment with either ipilimumab or, for patients with BRAF-mutated tumors, an oral BRAF inhibitor at a dose of 2 mg/kg every 3 weeks. Thus far, more than 2,000 melanoma patients have been evaluated in clinical trials with pembrolizumab.“
