Skin Cancer Prevention: A Guide to Protection and Risk Factors

Posted on June 1, 2025 in Skin Cancer

Written by Wittlinger, Claire E.

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Skin cancer is the most common cancer in the United States, with over 5 million people affected each year. The encouraging news? Most skin cancers are highly preventable when you understand the risk factors and take simple protective steps.

Whether you have fair skin that burns easily, spend time outdoors regularly, or have a family history of skin cancer, this guide will help you understand your risk and learn practical ways to protect yourself and your loved ones.

Understanding Skin Cancer and Your Risk

Skin cancer develops when skin cells are damaged by ultraviolet (UV) radiation from the sun or tanning beds. This damage can accumulate over years, from both prolonged outdoor exposure and everyday activities like walking to your car or checking the mail.

The Three Main Types of Skin Cancer

Basal Cell Carcinoma (BCC)

The most common type of skin cancer, developing in the bottom layer of the epidermis. BCCs are the least dangerous of the three main types and rarely spread to other parts of the body, but they can be disfiguring if left untreated.

Squamous Cell Carcinoma (SCC)

Less common than basal cell carcinoma but more dangerous. SCCs develop in the middle layer of skin and are more likely to spread if not treated promptly.

Melanoma

The rarest but most serious type of skin cancer. Melanoma develops in melanocyte cells (which produce skin pigment) and is most likely to spread to other parts of the body. When caught early, melanoma is highly treatable with a 99% five-year survival rate.

Key Risk Factors for Skin Cancer

Understanding your personal risk factors can help you take appropriate protective measures. Some factors you can control, while others are part of your genetic makeup.

Genetic Risk Factors (You're Born With)

  • Fair skin complexion that burns easily or doesn’t tan well
  • Light-colored eyes (blue, green, or hazel)
  • Blonde or red hair
  • Family history of skin cancer or unusual moles
  • Having 50 or more moles on your body
  • Skin that freckles easily in the sun

Environmental and Lifestyle Risk Factors (You Can Control)

  • History of sunburns, especially severe blistering sunburns during childhood or adolescence
  • Excessive sun exposure over time, even without burning
  • Indoor or outdoor tanning use
  • Living in sunny climates or high altitudes
  • Occupational sun exposure (outdoor workers)
  • Previous skin cancer diagnosis

Other Important Risk Factors

  • Weakened immune system due to illness or medications
  • Certain medications that increase sun sensitivity (ask your doctor or pharmacist)
  • Previous radiation treatment
  • Exposure to arsenic or other harmful chemicals

Essential Prevention Strategies

The good news about skin cancer is that it’s largely preventable.

Seek Shade During Peak Hours

The sun’s skin damaging rays are strongest between 10 AM and 4 PM. A simple way to tell if UV rays are intense: if your shadow is shorter than your actual height, seek shade or increase protection.

Cover Up with Protective Clothing

  • Long-sleeved shirts and pants when possible
  • Wide-brimmed hats that protect your face, ears, and neck (baseball caps don’t provide adequate protection)
  • UV-blocking sunglasses to protect your eyes and surrounding skin
  • Look for UPF (Ultraviolet Protection Factor) labeled clothing for enhanced protection

Avoid Tanning Beds Completely

Indoor tanning increases your risk of developing melanoma by 75% when used before age 35. There is no such thing as a “safe tan” from tanning beds. If you want a bronzed look, consider self-tanning products instead.

Practice Year-Round Protection

UV rays can penetrate clouds and reflect off water, snow, and sand. You need protection even on cloudy days and during winter months.

Daily Sun Protection Guidelines

What to Look For:

Choosing and Using Sunscreen Properly

  • Broad-spectrum protection (protects against both UVA and UVB rays)
  • SPF 30 or higher for daily use
  • Water-resistant formula for outdoor activities
applying sunscreen for sun protection against skin cancer

How to Apply:

  • Use 1 ounce (about 2 tablespoons) for your entire body
  • Apply 30 minutes before sun exposure
  • Reapply every 2 hours or immediately after swimming, sweating, or toweling off
  • Don’t forget often-missed spots: ears, back of neck, tops of feet, and hairline

Additional Protection Tips

  • UV rays can penetrate glass, so consider protection during long car rides
  • Certain medications can increase sun sensitivity – check with your pharmacist
  • Protect children carefully – childhood sunburns significantly increase lifetime skin cancer risk
  • Use lip balm with SPF to protect this often-forgotten area

Early Detection and Self-Exams

Early detection dramatically improves treatment outcomes. The five-year survival rate for melanoma caught early is about 99%.

Monthly Self-Examination

Perform a head-to-toe skin examination once a month:

  • Use good lighting and a full-length mirror
  • Check all areas including between toes, soles of feet, and scalp
  • Ask a partner to help examine hard-to-see areas like your back
  • Take photos of moles or spots to track changes over time

The ABCDE Warning Signs

Watch for these changes in moles or spots:

  • Asymmetry: One half doesn’t match the other
  • Border irregularity: Edges are ragged or blurred
  • Color variation: Multiple colors or uneven color distribution
  • Diameter: Larger than 6mm (size of a pencil eraser)
  • Evolving: Any change in size, shape, color, or texture

Additional Warning Signs

  • A sore that doesn’t heal within 2-3 weeks
  • New growth that bleeds, crusts, or itches
  • A spot that looks different from your other moles
  • Redness or swelling beyond the border of a mole

Special Considerations

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If You've Had Skin Cancer Before

Having a previous skin cancer diagnosis significantly increases your risk of developing new skin cancers, making ongoing vigilance essential. Your dermatologist will likely recommend more frequent follow-up appointments to monitor for new growths or changes in existing moles. This is also the time to become your own best advocate by being extra careful about sun protection and performing monthly self-examinations religiously. Any new spots, changes in existing moles, or areas that look different from your other skin should be reported to your healthcare provider immediately rather than waiting for your next scheduled appointment.

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Cancer Treatment and Sun Sensitivity

If you’re currently undergoing cancer treatment in Charlotte, it’s important to understand that many therapies can make your skin much more sensitive to UV radiation. Chemotherapy, radiation therapy, and certain medications can all increase your risk of severe sunburn and skin damage. Before starting treatment, discuss sun sensitivity risks with your care team and ask for specific guidance on protection strategies. During treatment, you may need to rely more heavily on protective clothing and shade rather than sunscreen alone, as some treatments can make skin more reactive to topical products. Additionally, be aware that medications like certain antibiotics, anti-inflammatory drugs, and even some herbal supplements can increase photosensitivity.

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Protecting Your Family

Teaching skin cancer prevention to your family, especially children, creates healthy habits that last a lifetime. Children under 6 months should be kept out of direct sunlight entirely, as their skin is too delicate for sunscreen and their natural protective mechanisms aren’t fully developed. For older children, make sun protection a natural part of daily routines rather than something reserved for beach days or summer activities. Children learn by watching, so when they see you applying sunscreen, wearing hats, and seeking shade, these behaviors become normal rather than burdensome. Start conversations about sun safety early, explaining why protection matters in age-appropriate ways, and praise them when they remember to protect themselves.

Beyond Basic Prevention

Nutrition and Lifestyle Factors

While sun protection is the most important factor, some research suggests:

  • Antioxidant-rich foods may provide some protective benefits
  • Regular exercise supports overall immune function
  • Avoiding smoking reduces skin cancer risk
  • Maintaining a healthy weight supports overall cancer prevention

Stay Informed About Research

Skin cancer prevention continues to evolve with new research. However, be cautious about:

  • Unproven supplements claiming to prevent skin cancer
  • Social media misinformation about sun exposure
  • Products making unrealistic claims about protection

Making Prevention a Habit

The key to effective skin cancer prevention is making protective behaviors part of your daily routine:

  • Apply sunscreen every morning as part of your routine
  • Keep protective items handy – sunscreen in your car, hat by the door
  • Set phone reminders for reapplication during outdoor activities
  • Schedule annual skin checks just like other preventive healthcare
  • Teach family members about protection and warning signs

Skin cancer is serious, but it’s also one of the most preventable cancers. By understanding your risk factors, practicing consistent sun protection, and staying vigilant about changes in your skin, you can significantly reduce your risk.

Remember that sun damage is cumulative – it’s never too late to start protecting yourself, and every protective step you take matters. If you have concerns about your skin or notice any changes, don’t hesitate to contact a healthcare provider. Early detection and treatment lead to the best outcomes.

At SERO, we understand that a cancer diagnosis can be overwhelming. Our radiation oncologists work closely with dermatologists and other specialists to provide comprehensive care for patients with skin cancer. If you’ve been diagnosed with skin cancer and need radiation therapy, our team is here to support you with expert, compassionate care throughout your treatment journey.